What are the novel findings of this work?
At 19–23weeks’ gestation, twin compared with singleton pregnancy is associated with an increase in cardiac output and reduction in left ventricular systolic and diastolic Doppler function. Cardiac changes are more accentuated in dichorionic compared with monochorionic twin pregnancies.
What are the clinical implications of this work?
Maternal cardiovascular adaptations seen in midgestation in twin pregnancy resemble those encountered in singleton pregnancy later in gestation and are mostly related to changes in loading conditions. These findings support the plasticity of the maternal cardiovascular system and its increased ability for remodeling in response to volume loading, without evidence of decompensation.